KMID : 0613820190290101111
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Journal of Life Science 2019 Volume.29 No. 10 p.1111 ~ p.1119
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Antioxidant and ¥á-Glucosidase Inhibition Activity of Solvent Fractions from Prunus mume Ethanol Extract
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Kim Jeong-Ho
Cho Hyun-Dong Won Yeong-Seon Park Wool-Lim Min Hye-Ji Han Sim-Hee Moon Kwang-Deog Seo Kwon-Il
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Abstract
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Prunus mume, known as maesil in Korea, has been widely cultivated in East Asia and used as medication and food. However, because most of the previous studies concerning P. mume had been investigated its under extract state, detailed studies are still required for its extensive utilization. In this study, we evaluated the antioxidant and ¥á-glucosidase inhibitory activities of solvent fractions of P. mume ethanol extracts. The ethyl acetate fraction showed higher DPPH radical scavenging activity, ABTS radical scavenging activity, reducing power, and hydrogen peroxide scavenging activity than other fractions. The DPPH radical scavenging activities of ethyl acetate fraction was 67.79%; ABTS radical scavenging activity was 60.03%; reducing power (OD670) was 1.26; and hydrogen peroxide scavenging activity was 93.18% at 500 ¥ìg/ml. Also, the ethyl acetate and methanol fraction showed effective levels of ¥á-glucosidase inhibition activity (69.25% and 72.29% at 500 ¥ìg/ml). Total polyphenol contents and total flavonoid contents of the ethyl acetate fraction were 88.28 mg/g (gallic acid equivalent) and 70.38 mg/g (quercetin equivalent), respectively. These results suggest that the physiological activities of the ethyl acetate fraction are associated with its polyphenol and flavonoid contents. Therefore, this study can be used as basic data for developing natural antioxidants and potential functional material using P. mume.
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KEYWORD
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Antioxidant, ¥á-glucosidase, Prunus mume, solvent fraction
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